Neonatal colonization of rats induces immunological tolerance to bacterial antigens
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چکیده
منابع مشابه
Termination of Acquired Immunological Tolerance to Protein Antigens following Immunization with Altered Protein Antigens
Acquired tolerance to BSA in rabbits was terminated following the injection of certain preparations of altered BSA. Injections of Freund's adjuvant containing BSA complexed to anti-BSA, heat-denatured BSA, acetyl-BSA, picryl-BSA, or arsanil-BSA failed to terminate the tolerant state. Except in an occasional tolerant rabbit, injections of these preparations failed to cause the production of prec...
متن کاملNeonatal cord blood subsets and cytokine response to bacterial antigens.
We compared lymphocyte subsets and cytokine responses to bacteria among term, preterm infants, and adults. Lymphocyte subset percentages in cord blood (22 preterm, 27 term neonates) and peripheral blood from 21 adults and cytokine/chemokine interleukin (IL)-6, IL-8, IL-10, IL-12, interferon gamma (IFN gamma) responses to Escherichia coli, group B Streptococcus (GBS), Staphylococcus epidermidis,...
متن کاملBacterial colonization of toys in neonatal intensive care cots.
OBJECTIVES To investigate the bacteria and fungi contaminating toys in neonatal intensive care unit (NICU) cots, the colonization rates, and factors that influence them. METHODS A cross-sectional, longitudinal bacteriologic survey of all toys in the cots of infants in an NICU. All the toys in an infant's cot were cultured weekly for 4 weeks. Data were collected on the infant's postnatal age, ...
متن کاملCardiac tolerance to ischemia in neonatal spontaneously hypertensive rats.
Hypertension is the risk factor of serious cardiovascular diseases, such as ischemic heart disease and atherosclerosis. The aim of the present study was to analyze the development of cardiac tolerance to ischemia in neonatal spontaneously hypertensive rats (SHR) and possible protective effect of ischemic preconditioning (IP) or adaptation to intermittent high-altitude hypoxia (IHAH). For this p...
متن کاملInduction of immunological tolerance to soluble histocompatibility-2 antigens of mice.
Immunological tolerance to a soluble, partially purified fraction of histocompatibility (H)-2(a) antigen was induced in B10.D2 strain mice. The fraction used was obtained after chromatography on a Sephadex G-150 column. Tolerance of humoral-antibody formation (cytotoxins and hemagglutinins) was observed in mice injected with soluble antigen since birth, but cell-mediated immunity, as measured b...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 1999
ISSN: 0014-2980,1521-4141
DOI: 10.1002/(sici)1521-4141(199901)29:01<109::aid-immu109>3.0.co;2-s